Holistic Chemical Process Assessment
This presentation will point out some of the considerations and pitfalls that are involved in transferring an "optimized" laboratory chemical procedure to the pilot plant and into production. This includes controlling the heat of reaction, physical phenomena, material of construction, space-volume efficiency, and solvent recovery.
Whilst this is traditionally done by appointing an experienced engineer to manage the tech transfer, the newer approach is to supply the development chemist with the understanding to avoid future pitfalls, already at the lab stage. Even with this new perspective, there has been very little attempt to create quantitative tools that can give an objective assessment of the suitability of a chemical process for plant production.
In this presentation we will look at one such quantitative tool that is under development at Makhteshim-Adama to assess and compare competing processes.
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Dr. Doron Mason
Born in Israel in 1956.Married to Karen, with 5 children and 7 grandchildren.
Educated in England – Manchester and Leeds.
First degree from Leeds University, second degree from Ben Gurion University.
PhD under Yoel and Shlomo Magdassi 1988-92
"The Significance of Surface Chemistry in Phase Transfer Catalysis".
Employed by Makhteshim (now Makhteshim-Adama) since 1995 as a research group head. Over the last 6 years responsible for technology transfer between the lab and the pilot, including process assessment and optimization, early scale-up issues, reaction calorimetry and safety testing, corrosion, and polymorphism.